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KMID : 0383819800270030118
Tuberculosis and Respiratory Diseases
1980 Volume.27 No. 3 p.118 ~ p.121
First Case of Pulmonary Petriellidiosis in Korea
±è»óÀç(ÐÝßÆî§)/S. J. Kim
È«¿µÇ¥(ûóçµøõ)/À±¿µÀÚ(ëÅçµí­)/±è¼ºÁø(ÑÑà÷òå)/Y. P. Hong/Y. J. Yoon/S. C. Kim
Abstract
Petriellidium boydii (imperfect form, Monosporium apiospermum) is widely distributed
in nature, haying been isolated from the soils, from sea-water and from sewage. Such
ubiquity of the fungus in human habitat cause a variety of diseases in man and
animals. The fungus is an important etiologic agent of human eumycetomas, rarely of
meningitis and of pulmonary infections. There has been no record of the isolation of P.
boydii from nature in Korea and also no report of a case of petriellidiosis in Korea
previously. Therefore this is the first description of a case of pulmonary petriellidiosis in
Korea. The patient is a 30-year-old man residing in Seoul and he was under
unsuccessful tuberculosis chemotherapy mainly due to irregular drug ingestion and poor
regimen since his pulmonary tuberculosis had been diagnosed at a physical examination
for conscription in 1970. Introduction of powerful retreatment regimen,
rifampicin-cycloserine-kanamycin, started on October 1977 at the KIT-Clinic greatly
improved his chest roentgenograms, showing an apparent shrinkage of a large cavity in
the upper lobe of the left lung and no more acid fast bacilli in his sputum. Continuous
negativity of acid fast bacilli in his sputum since then apparently indicated a good
chemotherapy respense. However he complained intermittent hemoptysis since February
1980 and his sputum culture in Sabouraud's agar produced numerous Colonies of P.
boydii. The same fungus was continuously isolated from the sputum specimens
collected on April, May and September 1980. The patient serum produced more than 3
precipitin bands on immunodiffusion test using 10 titles concentrated culture filtrate
antigen. of p. boydii The serum also react weakly with similarly prepared antigens of A.
flavus and C. albicans, but not with antigens A. tumigatus and A. nidulans. The patient
might be infected currently or previously with A. flavus and C. albicans.
Unfortunately pulmonary function of the patient does not allow surgical excision of the
infected area.
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